CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01785
Pert ID:	BRD-K54233340
Compound Name:	dorsomorphin
Targets:	ACVR1\|BMPR1A\|BMPR1B\|EPHA2\|FKBP1A\|FLT1\|FLT3\|KDR\|LCK\|MKNK1\|PRKAA1\|RPS6KA1\|SRC
MoA:	AMPK inhibitor
SMILES:	C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5788	BRD-K54233340	HCC515	10 uM	6 h	0.0	0.0	0.0
6434	BRD-K54233340	VCAP	10 uM	24 h	0.0	0.0	0.0
9444	BRD-K54233340	AGS	10 uM	6 h	0.0	0.0	0.0
9750	BRD-K54233340	H1299	10 uM	6 h	0.0	0.0	0.0
10063	BRD-K54233340	HA1E	10 uM	6 h	0.0	0.0	0.0
10536	BRD-K54233340	HCT116	10 uM	6 h	-0.39	-1.31	1.71
10802	BRD-K54233340	HEPG2	10 uM	6 h	0.0	0.0	0.0
11067	BRD-K54233340	HT29	10 uM	6 h	0.0	0.0	0.0
11283	BRD-K54233340	MCF??7.00	10 uM	6 h	0.0	0.0	0.0
11511	BRD-K54233340	NCIH2073	10 uM	6 h	0.0	0.0	0.0
11782	BRD-K54233340	NCIH508	10 uM	6 h	-0.41	-1.39	2.02
12071	BRD-K54233340	NCIH596	10 uM	6 h	0.0	0.0	0.0
12334	BRD-K54233340	NOMO1	10 uM	6 h	0.0	0.0	0.0
12611	BRD-K54233340	PC3	10 uM	6 h	0.0	0.0	0.0
12812	BRD-K54233340	SW480	10 uM	6 h	0.0	0.0	0.0
12967	BRD-K54233340	THP1	10 uM	6 h	0.0	0.0	0.0
13297	BRD-K54233340	U937	10 uM	6 h	0.0	0.0	0.0
44418	BRD-K54233340	A375	10 uM	6 h	0.0	0.0	0.0
44718	BRD-K54233340	A549	10 uM	6 h	0.0	0.0	0.0
44989	BRD-K54233340	ASC	10 uM	24 h	0.26	0.91	0.24
46105	BRD-K54233340	NPC	10 uM	24 h	0.0	0.0	0.0
46744	BRD-K54233340	SKB	10 uM	24 h	0.0	0.0	0.0
95981	BRD-K54233340	PHH	1.11 uM	24 h	0.0	0.0	0.0
99654	BRD-K54233340	U2OS	10 uM	6 h	0.0	0.0	0.0

Summary