CMap Candidate Details
Structure:
| CMap ID: | C01801 |
| Pert ID: | BRD-A64553394 |
| Compound Name: | DPI-201106 |
| Targets: | ADRB2 |
| MoA: | sodium channel activator |
| SMILES: | OC(COc1cccc2[nH]c(cc12)C#N)CN1CCN(CC1)C(c1ccccc1)c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 100267 | BRD-A64553394 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124578 | BRD-A64553394 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124615 | BRD-A64553394 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.81 | 0.13 |
| 124659 | BRD-A64553394 | HELA | 10 uM | 24 h | 0.2 | 0.82 | 0.0 | -0.35 | -1.17 | 1.12 |
| 124692 | BRD-A64553394 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.05 |
| 124724 | BRD-A64553394 | JURKAT | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.22 | 1.24 |
| 124761 | BRD-A64553394 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124797 | BRD-A64553394 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.96 | 0.44 |
| 124838 | BRD-A64553394 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124880 | BRD-A64553394 | THP1 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124915 | BRD-A64553394 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132688 | BRD-A64553394 | A549 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.26 |
| 132753 | BRD-A64553394 | HEK293 | 0.03 uM | 24 h | -0.26 | -1.09 | 0.31 | 0.0 | 0.0 | 0.0 |
| 132869 | BRD-A64553394 | MCF10A | 0.01 uM | 24 h | -0.23 | -0.97 | 0.11 | 0.0 | 0.0 | 0.0 |