CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01812
Pert ID:	BRD-K97158071
Compound Name:	droperidol
Targets:	ADRA1A\|DRD2\|DRD3\|DRD4\|HTR2A
MoA:	dopamine receptor antagonist
SMILES:	Fc1ccc(cc1)C(=O)CCCN1CCC(=CC1)n1c2ccccc2[nH]c1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5704	BRD-K97158071	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5965	BRD-K97158071	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
25456	BRD-K97158071	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39866	BRD-K97158071	ASC	10 uM	24 h	0.22	0.9	0.03	0.0	0.0	0.0
40960	BRD-K97158071	NEU	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.29
41285	BRD-K97158071	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41628	BRD-K97158071	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128227	BRD-K97158071	MCF10A	0.04 uM	24 h	0.18	0.77	0.0	0.0	0.0	0.0
128306	BRD-K97158071	MDAMB231	0.04 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
128334	BRD-K97158071	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135760	BRD-K97158071	A375	2.22 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.63
135777	BRD-K97158071	A549	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135814	BRD-K97158071	HA1E	0.74 uM	24 h	-0.21	-0.87	0.02	-0.28	-0.93	0.35
135853	BRD-K97158071	HEK293	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135901	BRD-K97158071	HELA	0.01 uM	24 h	-0.28	-1.17	0.48	0.0	0.0	0.0
135946	BRD-K97158071	HT29	0.08 uM	24 h	0.0	0.0	0.0	0.23	0.81	0.09
135990	BRD-K97158071	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	-0.36	-1.2	1.21
136031	BRD-K97158071	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136091	BRD-K97158071	THP1	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136136	BRD-K97158071	YAPC	2.22 uM	24 h	0.0	0.0	0.0	-0.24	-0.81	0.13

Summary