CMap Candidate Details
Structure:
| CMap ID: | C01818 |
| Pert ID: | BRD-K11558771 |
| Compound Name: | droxinostat |
| Targets: | HDAC6|HDAC8 |
| MoA: | HDAC inhibitor |
| SMILES: | Cc1cc(Cl)ccc1OCCCC(=O)NO |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49811 | BRD-K11558771 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50154 | BRD-K11558771 | HA1E | 10 uM | 6 h | -0.27 | -1.11 | 0.36 | 0.0 | 0.0 | 0.0 |
| 50341 | BRD-K11558771 | HCC515 | 10 uM | 6 h | 0.23 | 0.97 | 0.08 | 0.25 | 0.88 | 0.19 |
| 50505 | BRD-K11558771 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.19 | 1.05 |
| 50736 | BRD-K11558771 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.77 | 0.09 |
| 50912 | BRD-K11558771 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.95 | 0.41 |
| 51129 | BRD-K11558771 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95977 | BRD-K11558771 | PHH | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96113 | BRD-K11558771 | A549 | 10 uM | 24 h | -0.22 | -0.91 | 0.05 | 0.26 | 0.9 | 0.22 |