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CMap Candidate Details

Structure:
CMap ID: C00182
Pert ID: BRD-K51751936
Compound Name: alfadolone-acetate
Targets:
MoA: benzodiazepine receptor agonist
SMILES: CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2894 BRD-K51751936 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
3224 BRD-K51751936 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3628 BRD-K51751936 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3825 BRD-K51751936 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41781 BRD-K51751936 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41943 BRD-K51751936 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42381 BRD-K51751936 ASC 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
42702 BRD-K51751936 HEPG2 10 uM 6 h -0.23 -0.97 0.1 -0.24 -0.82 0.14
43004 BRD-K51751936 HT29 10 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
43198 BRD-K51751936 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43569 BRD-K51751936 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.17
43869 BRD-K51751936 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99631 BRD-K51751936 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).