CMap Candidate Details
Structure:
| CMap ID: | C01823 |
| Pert ID: | BRD-K06221026 |
| Compound Name: | DUP-697 |
| Targets: | PTGS2 |
| MoA: | cyclooxygenase inhibitor |
| SMILES: | CS(=O)(=O)c1ccc(cc1)-c1cc(Br)sc1-c1ccc(F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 4188 | BRD-K06221026 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 4347 | BRD-K06221026 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.06 |
| 22089 | BRD-K06221026 | A375 | 10 uM | 6 h | 0.23 | 0.96 | 0.07 | 0.26 | 0.91 | 0.23 |
| 22109 | BRD-K06221026 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.32 | 1.71 |
| 22973 | BRD-K06221026 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 23280 | BRD-K06221026 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 23696 | BRD-K06221026 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 23961 | BRD-K06221026 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24279 | BRD-K06221026 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44831 | BRD-K06221026 | ASC | 10 uM | 24 h | -0.25 | -1.05 | 0.24 | 0.24 | 0.85 | 0.15 |
| 45946 | BRD-K06221026 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.9 | 0.29 |