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CMap Candidate Details

Structure:
CMap ID: C01841
Pert ID: BRD-K29359156
Compound Name: ebselen
Targets: ALB
MoA: cyclooxygenase inhibitor; glutathione peroxidase agonist; H+/K+-ATPase inhibitor; nitric oxide synthase inhibitor
SMILES: O=c1n([se]c2ccccc12)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22737 BRD-K29359156 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
23024 BRD-K29359156 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.5 15.35
24890 BRD-K29359156 HT29 10 uM 6 h 0.18 0.74 0.0 0.24 0.84 0.13
25500 BRD-K29359156 VCAP 10 uM 6 h 0.26 1.07 0.19 0.0 0.0 0.0
90851 BRD-K29359156 MCF10A 1.11 uM 12 h 0.0 0.0 0.0 0.0 0.0 0.0
119997 BRD-K29359156 A549 3.33 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
120030 BRD-K29359156 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120072 BRD-K29359156 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120156 BRD-K29359156 MCF??7.00 10 uM 24 h 0.18 0.76 0.0 0.0 0.0 0.0
120191 BRD-K29359156 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128797 BRD-K29359156 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128879 BRD-K29359156 YAPC 0.25 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).