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CMap Candidate Details

Structure:
CMap ID: C01845
Pert ID: BRD-K03353589
Compound Name: ecabet
Targets: NOXO1
MoA: gastrin inhibitor; urease inhibitor
SMILES: CC(C)c1cc2CC[C@H]3[C@@](C)(CCC[C@]3(C)c2cc1S(O)(=O)=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121740 BRD-K03353589 HA1E 1.11 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
121802 BRD-K03353589 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.91
121848 BRD-K03353589 PC3 1.11 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
121871 BRD-K03353589 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
129764 BRD-K03353589 A375 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129841 BRD-K03353589 HEK293 0.01 uM 24 h 0.23 0.96 0.07 0.28 0.99 0.39
129878 BRD-K03353589 HELA 0.03 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
129967 BRD-K03353589 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130007 BRD-K03353589 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130052 BRD-K03353589 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130123 BRD-K03353589 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).