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CMap Candidate Details

Structure:
CMap ID: C01855
Pert ID: BRD-K86892782
Compound Name: edoxudine
Targets:
MoA: DNA directed DNA polymerase inhibitor
SMILES: CCc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125571 BRD-K86892782 A375 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
125609 BRD-K86892782 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125642 BRD-K86892782 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125671 BRD-K86892782 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125691 BRD-K86892782 HT29 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
125720 BRD-K86892782 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125768 BRD-K86892782 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
125796 BRD-K86892782 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
125822 BRD-K86892782 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
125919 BRD-K86892782 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133691 BRD-K86892782 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133904 BRD-K86892782 MDAMB231 0.08 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
133938 BRD-K86892782 PC3 2.22 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
133968 BRD-K86892782 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).