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CMap Candidate Details

Structure:
CMap ID: C01897
Pert ID: BRD-K15010214
Compound Name: emedastine
Targets: HRH1
MoA: histamine receptor antagonist
SMILES: CCOCCn1c(nc2ccccc12)N1CCCN(C)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122268 BRD-K15010214 A375 0.125 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
122288 BRD-K15010214 A549 1.11 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
122304 BRD-K15010214 HA1E 3.33 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
122323 BRD-K15010214 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
122336 BRD-K15010214 HELA 1.11 uM 24 h 0.28 1.17 0.37 0.0 0.0 0.0
122346 BRD-K15010214 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
122372 BRD-K15010214 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122398 BRD-K15010214 MCF??7.00 10 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
122425 BRD-K15010214 MDAMB231 1.11 uM 24 h 0.23 0.96 0.07 -0.25 -0.83 0.16
122447 BRD-K15010214 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122491 BRD-K15010214 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122525 BRD-K15010214 YAPC 0.125 uM 24 h -0.22 -0.93 0.07 -0.4 -1.36 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).