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CMap Candidate Details

Structure:
CMap ID: C01921
Pert ID: BRD-K76534306
Compound Name: enrofloxacin
Targets:
MoA: bacterial DNA gyrase inhibitor
SMILES: CCN1CCN(CC1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4139 BRD-K76534306 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4485 BRD-K76534306 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
4718 BRD-K76534306 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5123 BRD-K76534306 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22339 BRD-K76534306 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23436 BRD-K76534306 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23754 BRD-K76534306 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37187 BRD-K76534306 A375 10 uM 6 h 0.0 0.0 0.0 0.33 1.15 0.89
37736 BRD-K76534306 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37944 BRD-K76534306 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38552 BRD-K76534306 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
38777 BRD-K76534306 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39003 BRD-K76534306 SKB 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
91274 BRD-K76534306 HUH7 10 uM 72 h 0.0 0.0 0.0 -0.26 -0.87 0.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).