CMap Candidate Details
Structure:
| CMap ID: | C01922 |
| Pert ID: | BRD-K83636919 |
| Compound Name: | entacapone |
| Targets: | COMT |
| MoA: | catechol O methyltransferase inhibitor |
| SMILES: | CCN(CC)C(=O)C(\C#N)=C\c1cc(O)c(O)c(c1)[N+]([O-])=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49899 | BRD-K83636919 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50248 | BRD-K83636919 | HA1E | 10 uM | 6 h | 0.19 | 0.81 | 0.0 | 0.23 | 0.81 | 0.09 |
| 50597 | BRD-K83636919 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50690 | BRD-K83636919 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.03 | 0.62 |
| 50867 | BRD-K83636919 | PC3 | 10 uM | 24 h | 0.16 | 0.69 | 0.0 | -0.37 | -1.23 | 1.25 |
| 51185 | BRD-K83636919 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91172 | BRD-K83636919 | HUH7 | 10 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |