CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01932
Pert ID:	BRD-K47554101
Compound Name:	eperezolid
Targets:
MoA:	bacterial 30S ribosomal subunit inhibitor
SMILES:	CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCN(CC2)C(=O)CO)c(F)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95366	BRD-K47554101	MCF??7.00	10 uM	48 h	0.33	1.39	1.02	0.0	0.0	0.0
95435	BRD-K47554101	U2OS	1.11 uM	48 h	0.19	0.8	0.0	0.25	0.88	0.19
125239	BRD-K47554101	A375	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125312	BRD-K47554101	HEK293	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125494	BRD-K47554101	PC3	1.11 uM	24 h	-0.19	-0.78	0.0	0.22	0.77	0.05
133363	BRD-K47554101	A549	0.08 uM	24 h	-0.26	-1.07	0.27	0.0	0.0	0.0
133388	BRD-K47554101	HA1E	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133421	BRD-K47554101	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133454	BRD-K47554101	HT29	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133483	BRD-K47554101	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133517	BRD-K47554101	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133553	BRD-K47554101	MDAMB231	0.03 uM	24 h	0.0	0.0	0.0	-0.3	-0.99	0.51
133606	BRD-K47554101	THP1	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133632	BRD-K47554101	YAPC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary