CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01937
Pert ID:	BRD-K50660797
Compound Name:	epicatechin-gallate-(-)
Targets:	BACE1\|FASN
MoA:	bacterial DNA gyrase inhibitor
SMILES:	Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5461	BRD-K50660797	HA1E	10 uM	6 h	0.25	1.03	0.13	0.31	1.1	0.69
5643	BRD-K50660797	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
6104	BRD-K50660797	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.27	-0.89	0.27
6199	BRD-K50660797	PC3	10 uM	24 h	-0.24	-1.01	0.17	0.31	1.09	0.67
6564	BRD-K50660797	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37167	BRD-K50660797	A375	10 uM	6 h	-0.21	-0.88	0.03	-0.24	-0.82	0.15
37394	BRD-K50660797	A549	10 uM	6 h	0.0	0.0	0.0	-0.2	-0.69	0.02
37681	BRD-K50660797	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37916	BRD-K50660797	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38092	BRD-K50660797	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38505	BRD-K50660797	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38739	BRD-K50660797	PHH	10 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.68
38966	BRD-K50660797	SKB	10 uM	24 h	0.23	0.94	0.06	0.0	0.0	0.0
99620	BRD-K50660797	U2OS	10 uM	6 h	-0.23	-0.95	0.09	0.0	0.0	0.0

Summary