CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01938
Pert ID:	BRD-K55591206
Compound Name:	epigallocatechin-gallate-(-)
Targets:	ELANE\|EP300\|FASN\|KAT2B\|MMP14\|MMP2
MoA:	bacterial DNA gyrase inhibitor
SMILES:	Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
25522	BRD-K55591206	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
25702	BRD-K55591206	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
25951	BRD-K55591206	A549	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.28
28908	BRD-K55591206	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
29240	BRD-K55591206	SKB	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.06	0.73
93657	BRD-K55591206	ASC	10 uM	24 h	0.19	0.81	0.0	0.34	1.21	1.15
93719	BRD-K55591206	CD34	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93761	BRD-K55591206	HA1E	0.12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93796	BRD-K55591206	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93846	BRD-K55591206	HEK293	0.37 uM	24 h	-0.2	-0.83	0.0	0.0	0.0	0.0
93890	BRD-K55591206	HELA	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93930	BRD-K55591206	HEPG2	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
93964	BRD-K55591206	HUVEC	10 uM	24 h	-0.22	-0.91	0.05	0.0	0.0	0.0
94030	BRD-K55591206	JURKAT	1.11 uM	24 h	-0.27	-1.11	0.36	-0.41	-1.37	2.02
94064	BRD-K55591206	MCF??7.00	0.12 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94108	BRD-K55591206	NEU	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94140	BRD-K55591206	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94195	BRD-K55591206	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94242	BRD-K55591206	SHSY5Y	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
94294	BRD-K55591206	SKL	3.33 uM	24 h	0.0	0.0	0.0	0.23	0.81	0.09
94341	BRD-K55591206	THP1	10 uM	24 h	0.32	1.31	0.78	0.0	0.0	0.0
94382	BRD-K55591206	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
119700	BRD-K55591206	HT29	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary