CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C01940
Pert ID:	BRD-K63126190
Compound Name:	epinephrine
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C\|ADRB1\|ADRB2\|ADRB3\|PAH\|TNF
MoA:	adrenergic receptor agonist; neurotransmitter
SMILES:	CNC[C@H](O)c1ccc(O)c(O)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125071	BRD-K63126190	MCF10A	10 uM	24 h	-0.32	-1.34	0.98	0.0	0.0	0.0
125107	BRD-K63126190	MDAMB231	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125155	BRD-K63126190	THP1	1.11 uM	24 h	-0.33	-1.39	1.09	-0.37	-1.24	1.3
125203	BRD-K63126190	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132975	BRD-K63126190	A375	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132993	BRD-K63126190	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133011	BRD-K63126190	HA1E	0.01 uM	24 h	-0.24	-1.01	0.16	0.0	0.0	0.0
133041	BRD-K63126190	HEK293	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133086	BRD-K63126190	HELA	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133113	BRD-K63126190	HT29	0.08 uM	24 h	0.23	0.97	0.08	0.0	0.0	0.0
133148	BRD-K63126190	JURKAT	0.08 uM	24 h	0.0	0.0	0.0	-0.43	-1.46	15.35
133221	BRD-K63126190	MCF??7.00	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133286	BRD-K63126190	PC3	2.22 uM	24 h	0.28	1.18	0.39	0.0	0.0	0.0

Summary