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CMap Candidate Details

Structure:
CMap ID: C00195
Pert ID: BRD-K86307448
Compound Name: allopurinol
Targets: XDH
MoA: xanthine oxidase inhibitor
SMILES: O=c1[nH]cnc2[nH]ncc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90778 BRD-K86307448 HPTEC 1000 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97944 BRD-K86307448 MCF??7.00 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97947 BRD-K86307448 P1A82 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126020 BRD-K86307448 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126102 BRD-K86307448 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 0.44 1.55 2.32
126154 BRD-K86307448 JURKAT 0.37 uM 24 h -0.31 -1.31 0.82 0.0 0.0 0.0
126205 BRD-K86307448 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126247 BRD-K86307448 MDAMB231 1.11 uM 24 h 0.25 1.05 0.17 -0.34 -1.14 1.05
126275 BRD-K86307448 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126324 BRD-K86307448 THP1 10 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
126350 BRD-K86307448 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134024 BRD-K86307448 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134053 BRD-K86307448 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134128 BRD-K86307448 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134167 BRD-K86307448 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134197 BRD-K86307448 HT29 0.25 uM 24 h 0.29 1.21 0.46 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).