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CMap Candidate Details

Structure:
CMap ID: C01957
Pert ID: BRD-A90547603
Compound Name: eptifibatide
Targets: ITGA2B|ITGB3
MoA: platelet aggregation inhibitor
SMILES: NC(=N)NCCCCC1NC(=O)CCSSCC(NC(=O)C2CCCN2C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CC(O)=O)NC(=O)CNC1=O)C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127738 BRD-A90547603 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127781 BRD-A90547603 A549 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
127861 BRD-A90547603 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127935 BRD-A90547603 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
127988 BRD-A90547603 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128048 BRD-A90547603 PC3 0.37 uM 24 h -0.26 -1.08 0.3 0.22 0.76 0.05
135525 BRD-A90547603 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135562 BRD-A90547603 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135609 BRD-A90547603 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135653 BRD-A90547603 JURKAT 2.22 uM 24 h 0.23 0.94 0.06 -0.25 -0.85 0.2
135692 BRD-A90547603 MCF??7.00 2.22 uM 24 h 0.17 0.69 0.0 0.0 0.0 0.0
135742 BRD-A90547603 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).