CMap Candidate Details
Structure:
| CMap ID: | C01960 |
| Pert ID: | BRD-K57754230 |
| Compound Name: | EPZ005687 |
| Targets: | EZH2 |
| MoA: | histone lysine methyltransferase inhibitor |
| SMILES: | Cc1cc(C)c(CNC(=O)c2cc(cc3n(ncc23)C2CCCC2)-c2ccc(CN3CCOCC3)cc2)c(=O)[nH]1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95727 | BRD-K57754230 | A375 | 6.66 uM | 6 h | -0.24 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |
| 95736 | BRD-K57754230 | MCF??7.00 | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95747 | BRD-K57754230 | NPC | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95757 | BRD-K57754230 | PC3 | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95780 | BRD-K57754230 | A549 | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95923 | BRD-K57754230 | YAPC | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.71 |