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CMap Candidate Details

Structure:
CMap ID: C02087
Pert ID: BRD-K78633253
Compound Name: EXO-1
Targets:
MoA: ARF inhibitor
SMILES: COC(=O)c1ccccc1NC(=O)c1ccc(F)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3391 BRD-K78633253 HCC515 10 uM 6 h -0.22 -0.92 0.06 0.26 0.91 0.23
3863 BRD-K78633253 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
13959 BRD-K78633253 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
14328 BRD-K78633253 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
14521 BRD-K78633253 HA1E 10 uM 24 h -0.25 -1.05 0.23 0.0 0.0 0.0
15394 BRD-K78633253 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15669 BRD-K78633253 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40061 BRD-K78633253 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40324 BRD-K78633253 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40868 BRD-K78633253 NEU 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.15
41185 BRD-K78633253 NPC 10 uM 24 h 0.2 0.85 0.01 0.25 0.89 0.2
41524 BRD-K78633253 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).