CMap Candidate Details
Structure:
| CMap ID: | C02093 |
| Pert ID: | BRD-A25619068 |
| Compound Name: | fadrozole |
| Targets: | CYP11B1|CYP19A1 |
| MoA: | aromatase inhibitor |
| SMILES: | N#Cc1ccc(cc1)C1CCCc2cncn12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51374 | BRD-A25619068 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95309 | BRD-A25619068 | A549 | 4 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95471 | BRD-A25619068 | U2OS | 0.05 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.48 |
| 120875 | BRD-A25619068 | A375 | 1.11 uM | 24 h | 0.2 | 0.85 | 0.01 | 0.2 | 0.71 | 0.02 |
| 120973 | BRD-A25619068 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121130 | BRD-A25619068 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129143 | BRD-A25619068 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129172 | BRD-A25619068 | HELA | 0.08 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129204 | BRD-A25619068 | HT29 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129232 | BRD-A25619068 | PC3 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.03 | 0.63 |