Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02096
Pert ID: BRD-K45033733
Compound Name: famciclovir
Targets:
MoA: DNA polymerase inhibitor
SMILES: CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5775 BRD-K45033733 HCC515 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
25512 BRD-K45033733 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37664 BRD-K45033733 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37907 BRD-K45033733 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38489 BRD-K45033733 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38727 BRD-K45033733 PHH 10 uM 24 h -0.27 -1.12 0.38 -0.24 -0.82 0.15
91313 BRD-K45033733 HUH7 10 uM 72 h 0.0 0.0 0.0 0.27 0.96 0.33
96342 BRD-K45033733 A375 10 uM 24 h 0.23 0.96 0.08 0.0 0.0 0.0
99553 BRD-K45033733 U2OS 10 uM 6 h -0.22 -0.9 0.04 0.18 0.62 0.0
125253 BRD-K45033733 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125269 BRD-K45033733 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125293 BRD-K45033733 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
125368 BRD-K45033733 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.86
125389 BRD-K45033733 JURKAT 1.11 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
125429 BRD-K45033733 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125483 BRD-K45033733 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125512 BRD-K45033733 THP1 1.11 uM 24 h -0.34 -1.44 1.43 -0.26 -0.88 0.25
125540 BRD-K45033733 YAPC 10 uM 24 h 0.17 0.69 0.0 -0.3 -1.01 0.57
133409 BRD-K45033733 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133503 BRD-K45033733 MCF10A 0.25 uM 24 h -0.21 -0.88 0.03 -0.22 -0.74 0.06
133538 BRD-K45033733 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).