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CMap Candidate Details

Structure:
CMap ID: C02139
Pert ID: BRD-A73368467
Compound Name: fexofenadine
Targets: HRH1
MoA: histamine receptor antagonist
SMILES: CC(C)(C(O)=O)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5735 BRD-A73368467 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.49
6385 BRD-A73368467 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37355 BRD-A73368467 A549 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
37544 BRD-A73368467 ASC 10 uM 24 h 0.25 1.03 0.13 -0.44 -1.48 15.35
37848 BRD-A73368467 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38389 BRD-A73368467 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
38659 BRD-A73368467 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38884 BRD-A73368467 SKB 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.78
126447 BRD-A73368467 HEK293 1.11 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
126525 BRD-A73368467 MCF10A 3.33 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
126557 BRD-A73368467 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126609 BRD-A73368467 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134355 BRD-A73368467 A375 0.01 uM 24 h 0.24 1.0 0.1 0.4 1.42 2.19
134406 BRD-A73368467 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134435 BRD-A73368467 HELA 2.22 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
134470 BRD-A73368467 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134514 BRD-A73368467 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134572 BRD-A73368467 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134629 BRD-A73368467 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).