CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02208
Pert ID:	BRD-K55127134
Compound Name:	fluphenazine
Targets:	CALM1\|DRD1\|DRD2\|DRD5\|HRH1\|HTR2A\|HTR6\|HTR7
MoA:	dopamine receptor antagonist
SMILES:	OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1132	BRD-K55127134	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7688	BRD-K55127134	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.1	0.86
7893	BRD-K55127134	HT29	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.38
23088	BRD-K55127134	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.32	1.12	0.77
23595	BRD-K55127134	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.75	0.06
88145	BRD-K55127134	VCAP	20 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
90950	BRD-K55127134	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
109013	BRD-K55127134	U2OS	20 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
124276	BRD-K55127134	A375	10 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.72
124289	BRD-K55127134	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124305	BRD-K55127134	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124322	BRD-K55127134	HEK293	10 uM	24 h	-0.23	-0.95	0.09	0.0	0.0	0.0
124359	BRD-K55127134	HELA	10 uM	24 h	0.0	0.0	0.0	0.26	0.93	0.27
124427	BRD-K55127134	JURKAT	10 uM	24 h	-0.23	-0.94	0.08	0.0	0.0	0.0
124453	BRD-K55127134	MCF10A	10 uM	24 h	-0.23	-0.97	0.1	0.0	0.0	0.0
124493	BRD-K55127134	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.43	1.51	2.28
124552	BRD-K55127134	YAPC	10 uM	24 h	0.28	1.17	0.37	0.0	0.0	0.0
132615	BRD-K55127134	THP1	0.01 uM	24 h	0.0	0.0	0.0	-0.23	-0.79	0.11

Summary