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CMap Candidate Details

Structure:
CMap ID: C02231
Pert ID: BRD-K54006094
Compound Name: formoterol
Targets: ADRB2
MoA: adrenergic receptor agonist
SMILES: COc1ccc(C[C@H](C)NC[C@@H](O)c2ccc(O)c(NC=O)c2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25252 BRD-K54006094 PC3 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.08
90320 BRD-K54006094 VCAP 10 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
96468 BRD-K54006094 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124288 BRD-K54006094 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124302 BRD-K54006094 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124421 BRD-K54006094 JURKAT 0.37 uM 24 h 0.26 1.08 0.2 0.28 0.99 0.4
124451 BRD-K54006094 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124468 BRD-K54006094 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124490 BRD-K54006094 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124550 BRD-K54006094 YAPC 0.04 uM 24 h -0.29 -1.21 0.59 -0.27 -0.9 0.29
132425 BRD-K54006094 HEK293 0.03 uM 24 h 0.24 1.02 0.12 -0.31 -1.05 0.7
132445 BRD-K54006094 HELA 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
132465 BRD-K54006094 HT29 0.74 uM 24 h -0.26 -1.09 0.33 -0.18 -0.62 0.0
132609 BRD-K54006094 THP1 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).