CMap Candidate Details
Structure:
| CMap ID: | C02243 |
| Pert ID: | BRD-A51382177 |
| Compound Name: | fosinopril |
| Targets: | ACE |
| MoA: | angiotensin converting enzyme inhibitor |
| SMILES: | CCC(=O)O[C@@H](OP(=O)(CCCCc1ccccc1)CC(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1)C(C)C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49949 | BRD-A51382177 | A549 | 10 uM | 6 h | -0.25 | -1.02 | 0.19 | 0.0 | 0.0 | 0.0 |
| 51100 | BRD-A51382177 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121560 | BRD-A51382177 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.89 | 0.27 |
| 121599 | BRD-A51382177 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121637 | BRD-A51382177 | HELA | 0.125 uM | 24 h | -0.23 | -0.96 | 0.1 | -0.35 | -1.17 | 1.11 |
| 121704 | BRD-A51382177 | YAPC | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.71 |
| 129631 | BRD-A51382177 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129660 | BRD-A51382177 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129690 | BRD-A51382177 | PC3 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.47 | -1.59 | 15.65 |