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CMap Candidate Details

Structure:
CMap ID: C02310
Pert ID: BRD-K50135270
Compound Name: GBR-12935
Targets: AGTR1|SLC6A3
MoA: dopamine uptake inhibitor
SMILES: C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2892 BRD-K50135270 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3220 BRD-K50135270 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3518 BRD-K50135270 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3818 BRD-K50135270 VCAP 10 uM 24 h 0.18 0.74 0.0 0.0 0.0 0.0
44594 BRD-K50135270 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
44978 BRD-K50135270 ASC 10 uM 24 h 0.22 0.91 0.03 -0.24 -0.8 0.12
45274 BRD-K50135270 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45542 BRD-K50135270 HT29 10 uM 6 h 0.0 0.0 0.0 0.45 1.58 2.36
45704 BRD-K50135270 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46094 BRD-K50135270 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46733 BRD-K50135270 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99612 BRD-K50135270 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).