CMap Candidate Details
Structure:
| CMap ID: | C00235 |
| Pert ID: | BRD-K59013864 |
| Compound Name: | AM-24 |
| Targets: | ALOX5 |
| MoA: | lipoxygenase inhibitor |
| SMILES: | Oc1c(I)cc(I)cc1I |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123803 | BRD-K59013864 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123842 | BRD-K59013864 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.06 | 0.73 |
| 123908 | BRD-K59013864 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123947 | BRD-K59013864 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123968 | BRD-K59013864 | HT29 | 10 uM | 24 h | 0.25 | 1.05 | 0.16 | 0.35 | 1.24 | 1.28 |
| 124009 | BRD-K59013864 | JURKAT | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.1 |
| 124062 | BRD-K59013864 | MCF10A | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.03 | 0.63 |
| 124130 | BRD-K59013864 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124191 | BRD-K59013864 | THP1 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124243 | BRD-K59013864 | YAPC | 0.04 uM | 24 h | 0.24 | 0.98 | 0.09 | -0.39 | -1.32 | 1.71 |
| 132169 | BRD-K59013864 | HA1E | 0.74 uM | 24 h | 0.2 | 0.84 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132257 | BRD-K59013864 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132301 | BRD-K59013864 | PC3 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |