Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02363
Pert ID: BRD-K80396088
Compound Name: gliquidone
Targets: ABCC8|KCNJ10|KCNJ8
MoA: sulfonylurea
SMILES: COc1ccc2c(c1)C(=O)N(CCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1)C(=O)C2(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3395 BRD-K80396088 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3870 BRD-K80396088 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39776 BRD-K80396088 ASC 10 uM 24 h -0.24 -1.0 0.14 0.25 0.9 0.22
40069 BRD-K80396088 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40877 BRD-K80396088 NEU 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
41195 BRD-K80396088 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41534 BRD-K80396088 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
125997 BRD-K80396088 HA1E 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
126025 BRD-K80396088 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126069 BRD-K80396088 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126110 BRD-K80396088 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126165 BRD-K80396088 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126253 BRD-K80396088 PC3 10 uM 24 h 0.22 0.91 0.04 0.25 0.9 0.21
126283 BRD-K80396088 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133996 BRD-K80396088 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134029 BRD-K80396088 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134084 BRD-K80396088 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
134173 BRD-K80396088 HT29 2.22 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
134219 BRD-K80396088 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
134249 BRD-K80396088 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
134304 BRD-K80396088 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).