CMap Candidate Details
Structure:
| CMap ID: | C00237 |
| Pert ID: | BRD-K59419204 |
| Compound Name: | AM-281 |
| Targets: | CNR1|CNR2|GPR55 |
| MoA: | cannabinoid receptor antagonist |
| SMILES: | Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCOCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6900 | BRD-K59419204 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7019 | BRD-K59419204 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7474 | BRD-K59419204 | HA1E | 10 uM | 6 h | 0.29 | 1.22 | 0.48 | -0.33 | -1.11 | 0.9 |
| 7699 | BRD-K59419204 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8019 | BRD-K59419204 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8169 | BRD-K59419204 | MCF??7.00 | 10 uM | 6 h | 0.24 | 1.01 | 0.12 | -0.21 | -0.72 | 0.04 |
| 8526 | BRD-K59419204 | PC3 | 10 uM | 6 h | 0.2 | 0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8714 | BRD-K59419204 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |