CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02376
Pert ID:	BRD-A81233518
Compound Name:	glycopyrrolate
Targets:	CHRM1\|CHRM2\|CHRM3\|CHRM4\|CHRM5
MoA:	acetylcholine receptor antagonist
SMILES:	C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
19221	BRD-A81233518	A549	10 uM	24 h	0.0	0.0	0.0	-0.41	-1.38	2.02
19883	BRD-A81233518	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
20213	BRD-A81233518	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
24995	BRD-A81233518	MCF??7.00	10 uM	24 h	-0.24	-1.01	0.17	0.26	0.92	0.25
25481	BRD-A81233518	VCAP	10 uM	6 h	-0.24	-0.98	0.12	-0.35	-1.17	1.11
126455	BRD-A81233518	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126561	BRD-A81233518	MDAMB231	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134359	BRD-A81233518	A375	0.01 uM	24 h	0.0	0.0	0.0	0.23	0.82	0.1
134410	BRD-A81233518	HA1E	0.25 uM	24 h	0.27	1.14	0.32	0.33	1.18	0.97
134439	BRD-A81233518	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134475	BRD-A81233518	HT29	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134522	BRD-A81233518	HUVEC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134548	BRD-A81233518	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134634	BRD-A81233518	PC3	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134658	BRD-A81233518	YAPC	0.01 uM	24 h	0.24	1.02	0.13	-0.22	-0.75	0.07

Summary