CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02394
Pert ID:	BRD-K65285700
Compound Name:	GP1a
Targets:	CNR2
MoA:	cannabinoid receptor agonist
SMILES:	Cc1ccc-2c(Cc3c(nn(c-23)-c2ccc(Cl)cc2Cl)C(=O)NN2CCCCC2)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4132	BRD-K65285700	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4586	BRD-K65285700	HCC515	10 uM	6 h	0.0	0.0	0.0	-0.26	-0.89	0.27
4949	BRD-K65285700	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44604	BRD-K65285700	A549	10 uM	24 h	0.0	0.0	0.0	-0.23	-0.78	0.09
45003	BRD-K65285700	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45294	BRD-K65285700	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.31	-1.03	0.65
45557	BRD-K65285700	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45710	BRD-K65285700	MCF??7.00	10 uM	24 h	-0.23	-0.97	0.11	0.27	0.94	0.29
46116	BRD-K65285700	NPC	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.67
46431	BRD-K65285700	PHH	10 uM	24 h	-0.25	-1.05	0.23	0.0	0.0	0.0
46756	BRD-K65285700	SKB	10 uM	24 h	0.23	0.97	0.08	-0.29	-0.98	0.48
96447	BRD-K65285700	A375	10 uM	24 h	-0.27	-1.12	0.38	-0.19	-0.65	0.01
96516	BRD-K65285700	PC3	10 uM	24 h	0.0	0.0	0.0	0.25	0.87	0.17
99341	BRD-K65285700	U2OS	10 uM	6 h	-0.23	-0.94	0.08	-0.2	-0.66	0.01
136399	BRD-K65285700	SHSY5Y	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary