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CMap Candidate Details

Structure:
CMap ID: C02400
Pert ID: BRD-K12120659
Compound Name: GR-144053
Targets: ITGA2B|ITGB3
MoA: integrin antagonist
SMILES: NC(=N)c1ccc(cc1)N1CCN(CC1)C1CCN(CC(O)=O)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1548 BRD-K12120659 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2082 BRD-K12120659 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2376 BRD-K12120659 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2538 BRD-K12120659 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42061 BRD-K12120659 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42299 BRD-K12120659 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42632 BRD-K12120659 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42935 BRD-K12120659 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43295 BRD-K12120659 MCF??7.00 10 uM 6 h -0.24 -1.01 0.16 -0.28 -0.94 0.37
43491 BRD-K12120659 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43795 BRD-K12120659 PHH 10 uM 24 h 0.25 1.05 0.17 0.21 0.75 0.04
97284 BRD-K12120659 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.29
97339 BRD-K12120659 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100089 BRD-K12120659 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).