CMap Candidate Details
Structure:
| CMap ID: | C02406 |
| Pert ID: | BRD-A10967948 |
| Compound Name: | granisetron |
| Targets: | HTR3A |
| MoA: | serotonin receptor antagonist |
| SMILES: | CN1C2CCCC1CC(C2)NC(=O)c1nn(C)c2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121164 | BRD-A10967948 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121200 | BRD-A10967948 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.14 | 0.87 |
| 121234 | BRD-A10967948 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121326 | BRD-A10967948 | PC3 | 0.04 uM | 24 h | -0.27 | -1.12 | 0.39 | 0.0 | 0.0 | 0.0 |
| 129267 | BRD-A10967948 | HELA | 2.22 uM | 24 h | -0.28 | -1.16 | 0.47 | 0.0 | 0.0 | 0.0 |
| 129313 | BRD-A10967948 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129346 | BRD-A10967948 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129384 | BRD-A10967948 | YAPC | 0.03 uM | 24 h | -0.24 | -1.0 | 0.15 | 0.0 | 0.0 | 0.0 |