CMap Candidate Details
Structure:
CMap ID: | C02426 |
Pert ID: | BRD-K04923131 |
Compound Name: | GSK-3-inhibitor-IX |
Targets: | GSK3A|GSK3B |
MoA: | glycogen synthase kinase inhibitor; lipoxygenase inhibitor |
SMILES: | O\N=C1/C(Nc2ccccc12)=C1/C(=O)Nc2cc(Br)ccc12 |
InchiKey: | |
Compound Aliases: |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
33887 | BRD-K04923131 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.96 | 0.43 |
34030 | BRD-K04923131 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.7 | 0.01 |
34543 | BRD-K04923131 | HCC515 | 10 uM | 6 h | -0.17 | -0.72 | 0.0 | -0.35 | -1.19 | 1.16 |
34813 | BRD-K04923131 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
35080 | BRD-K04923131 | HT29 | 10 uM | 6 h | 0.17 | 0.71 | 0.0 | -0.35 | -1.19 | 1.15 |
35379 | BRD-K04923131 | MCF??7.00 | 10 uM | 6 h | 0.16 | 0.67 | 0.0 | 0.0 | 0.0 | 0.0 |
36054 | BRD-K04923131 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.4 | -1.33 | 1.81 |
36186 | BRD-K04923131 | PHH | 10 uM | 24 h | 0.23 | 0.96 | 0.08 | 0.0 | 0.0 | 0.0 |
36479 | BRD-K04923131 | SKB | 10 uM | 24 h | 0.31 | 1.29 | 0.66 | 0.22 | 0.77 | 0.06 |
36941 | BRD-K04923131 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
91530 | BRD-K04923131 | BT20 | 0.37 uM | 6 h | 0.32 | 1.31 | 0.78 | -0.24 | -0.8 | 0.12 |
91569 | BRD-K04923131 | HS578T | 10 uM | 24 h | 0.23 | 0.96 | 0.07 | 0.0 | 0.0 | 0.0 |
91616 | BRD-K04923131 | MCF10A | 10 uM | 24 h | 0.32 | 1.34 | 0.89 | 0.0 | 0.0 | 0.0 |
91682 | BRD-K04923131 | MDAMB231 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
91765 | BRD-K04923131 | SKBR3 | 10 uM | 6 h | 0.22 | 0.93 | 0.05 | 0.24 | 0.85 | 0.14 |
97320 | BRD-K04923131 | HAP1 | 3.33 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.0 | 0.0 | 0.0 |
98741 | BRD-K04923131 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.1 | 0.7 |
98862 | BRD-K04923131 | NEU | 10 uM | 24 h | 0.2 | 0.84 | 0.0 | 0.24 | 0.86 | 0.16 |
118380 | BRD-K04923131 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
118451 | BRD-K04923131 | HA1E | 3.33 uM | 24 h | 0.21 | 0.87 | 0.01 | 0.0 | 0.0 | 0.0 |