CMap Candidate Details
Structure:
| CMap ID: | C02446 |
| Pert ID: | BRD-K89464729 |
| Compound Name: | GSK269962 |
| Targets: | ROCK1|ROCK2 |
| MoA: | rho associated kinase inhibitor |
| SMILES: | CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc12)-c1nonc1N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 117654 | BRD-K89464729 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.1 |
| 117702 | BRD-K89464729 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117748 | BRD-K89464729 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117798 | BRD-K89464729 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 117848 | BRD-K89464729 | HEPG2 | 10 uM | 24 h | 0.22 | 0.91 | 0.03 | -0.25 | -0.83 | 0.17 |
| 117898 | BRD-K89464729 | HT29 | 10 uM | 24 h | -0.25 | -1.03 | 0.2 | 0.0 | 0.0 | 0.0 |
| 117946 | BRD-K89464729 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 117993 | BRD-K89464729 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |