CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02465
Pert ID:	BRD-K62736196
Compound Name:	guanaben-acetate
Targets:	ADRA2A\|ADRA2B\|ADRA2C
MoA:	adrenergic receptor agonist
SMILES:	NC(=N)N\N=C\c1c(Cl)cccc1Cl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5349	BRD-K62736196	HA1E	10 uM	24 h	0.25	1.02	0.13	-0.28	-0.93	0.34
5660	BRD-K62736196	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5938	BRD-K62736196	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.4	1.4	2.18
6043	BRD-K62736196	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6207	BRD-K62736196	PC3	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.13	0.99
6395	BRD-K62736196	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39154	BRD-K62736196	A375	10 uM	6 h	0.0	0.0	0.0	0.28	0.98	0.39
39469	BRD-K62736196	A549	10 uM	6 h	0.22	0.93	0.05	0.0	0.0	0.0
39727	BRD-K62736196	ASC	10 uM	24 h	0.19	0.8	0.0	-0.36	-1.21	1.24
40625	BRD-K62736196	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40838	BRD-K62736196	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41145	BRD-K62736196	NPC	10 uM	24 h	0.0	0.0	0.0	0.31	1.11	0.73
41483	BRD-K62736196	SKB	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.51
91017	BRD-K62736196	HUH7	15 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary