CMap Candidate Details
Structure:
| CMap ID: | C02466 |
| Pert ID: | BRD-A14262390 |
| Compound Name: | guanadrel |
| Targets: | SLC6A2 |
| MoA: | adrenergic inhibitor |
| SMILES: | NC(=N)NCC1COC2(CCCCC2)O1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122258 | BRD-A14262390 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122299 | BRD-A14262390 | HA1E | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122319 | BRD-A14262390 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.2 | 1.21 |
| 122365 | BRD-A14262390 | MCF10A | 3.33 uM | 24 h | -0.18 | -0.74 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122392 | BRD-A14262390 | MCF??7.00 | 0.04 uM | 24 h | -0.23 | -0.97 | 0.1 | -0.29 | -0.97 | 0.45 |
| 122442 | BRD-A14262390 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122481 | BRD-A14262390 | THP1 | 0.04 uM | 24 h | -0.26 | -1.07 | 0.27 | 0.0 | 0.0 | 0.0 |
| 122519 | BRD-A14262390 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130561 | BRD-A14262390 | A549 | 0.25 uM | 24 h | -0.24 | -1.02 | 0.18 | 0.0 | 0.0 | 0.0 |
| 130673 | BRD-A14262390 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130713 | BRD-A14262390 | HT29 | 0.01 uM | 24 h | 0.24 | 1.0 | 0.1 | -0.24 | -0.81 | 0.13 |
| 130787 | BRD-A14262390 | MDAMB231 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.71 |