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CMap Candidate Details

Structure:
CMap ID: C02481
Pert ID: BRD-K10705233
Compound Name: GW-405833
Targets: CNR2
MoA: cannabinoid receptor agonist
SMILES: COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8910 BRD-K10705233 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9179 BRD-K10705233 A549 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9361 BRD-K10705233 AGS 40 uM 6 h 0.28 1.18 0.4 -0.3 -1.0 0.55
9668 BRD-K10705233 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10033 BRD-K10705233 HA1E 40 uM 6 h 0.0 0.0 0.0 0.19 0.68 0.01
10283 BRD-K10705233 HCC515 40 uM 6 h 0.0 0.0 0.0 -0.46 -1.54 15.35
10462 BRD-K10705233 HCT116 40 uM 6 h 0.0 0.0 0.0 -0.35 -1.19 1.15
10732 BRD-K10705233 HEPG2 40 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.3
10944 BRD-K10705233 HT29 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11265 BRD-K10705233 MCF??7.00 40 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
11420 BRD-K10705233 NCIH2073 40 uM 6 h 0.0 0.0 0.0 -0.34 -1.16 1.11
11711 BRD-K10705233 NCIH508 40 uM 6 h -0.22 -0.92 0.06 0.37 1.32 1.66
12268 BRD-K10705233 NOMO1 40 uM 6 h -0.28 -1.17 0.49 0.0 0.0 0.0
12472 BRD-K10705233 PC3 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12732 BRD-K10705233 SW480 40 uM 6 h 0.23 0.97 0.08 0.0 0.0 0.0
12986 BRD-K10705233 THP1 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13211 BRD-K10705233 U937 40 uM 6 h 0.17 0.72 0.0 0.22 0.79 0.08
13581 BRD-K10705233 VCAP 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44851 BRD-K10705233 ASC 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
45966 BRD-K10705233 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46286 BRD-K10705233 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46602 BRD-K10705233 SKB 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
100070 BRD-K10705233 U2OS 10 uM 6 h -0.18 -0.77 0.0 0.22 0.78 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).