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CMap Candidate Details

Structure:
CMap ID: C02488
Pert ID: BRD-K79930101
Compound Name: GW-583340
Targets: EGFR|ERBB2
MoA: EGFR inhibitor
SMILES: CS(=O)(=O)CCNCc1nc(cs1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1780 BRD-K79930101 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2128 BRD-K79930101 HCC515 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.34
2184 BRD-K79930101 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2672 BRD-K79930101 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41846 BRD-K79930101 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42149 BRD-K79930101 A549 10 uM 6 h 0.22 0.92 0.04 0.0 0.0 0.0
42480 BRD-K79930101 ASC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
42789 BRD-K79930101 HEPG2 10 uM 6 h -0.24 -0.99 0.14 -0.24 -0.81 0.12
43082 BRD-K79930101 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43237 BRD-K79930101 MCF??7.00 10 uM 24 h -0.26 -1.07 0.27 -0.3 -1.01 0.57
43654 BRD-K79930101 NPC 10 uM 24 h -0.25 -1.02 0.19 -0.32 -1.07 0.77
43957 BRD-K79930101 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
44209 BRD-K79930101 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).