CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02498
Pert ID:	BRD-K24240364
Compound Name:	GYKI-52466
Targets:	GRIA1\|GRIA2\|GRIA3\|GRIA4
MoA:	glutamate receptor antagonist
SMILES:	CC1=NN=C(c2ccc(N)cc2)c2cc3OCOc3cc2C1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2855	BRD-K24240364	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3166	BRD-K24240364	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3477	BRD-K24240364	PC3	10 uM	24 h	0.0	0.0	0.0	-0.37	-1.26	1.35
3754	BRD-K24240364	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44345	BRD-K24240364	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44552	BRD-K24240364	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45206	BRD-K24240364	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.28	0.98	0.39
45472	BRD-K24240364	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45793	BRD-K24240364	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
46021	BRD-K24240364	NPC	10 uM	24 h	0.22	0.91	0.03	0.26	0.91	0.23
46339	BRD-K24240364	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99768	BRD-K24240364	U2OS	10 uM	6 h	-0.26	-1.07	0.27	-0.37	-1.25	1.35

Summary