CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02536
Pert ID:	BRD-K99792991
Compound Name:	hexachlorophene
Targets:	GLUD1\|SDHD
MoA:	potassium channel activator
SMILES:	Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
52942	BRD-K99792991	HEPG2	40 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
53338	BRD-K99792991	MCF10A	30 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
95343	BRD-K99792991	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
95416	BRD-K99792991	U2OS	10 uM	48 h	0.0	0.0	0.0	0.25	0.88	0.18
98782	BRD-K99792991	NPC	10 uM	24 h	0.0	0.0	0.0	0.24	0.86	0.15
98962	BRD-K99792991	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127752	BRD-K99792991	A375	1.11 uM	24 h	-0.3	-1.24	0.64	-0.2	-0.67	0.02
127797	BRD-K99792991	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
127830	BRD-K99792991	HA1E	3.33 uM	24 h	0.0	0.0	0.0	0.31	1.1	0.69
127880	BRD-K99792991	HEK293	10 uM	24 h	0.0	0.0	0.0	0.23	0.8	0.08
127904	BRD-K99792991	HT29	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.02	0.61
127954	BRD-K99792991	HUVEC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128055	BRD-K99792991	PC3	10 uM	24 h	0.25	1.05	0.16	0.0	0.0	0.0
128087	BRD-K99792991	YAPC	3.33 uM	24 h	0.0	0.0	0.0	-0.24	-0.82	0.14
135581	BRD-K99792991	HELA	2.22 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.9
135672	BRD-K99792991	JURKAT	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary