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CMap Candidate Details

Structure:
CMap ID: C02545
Pert ID: BRD-A97730597
Compound Name: hexylcaine
Targets: SCN10A|SCN5A
MoA: sodium channel blocker
SMILES: CC(CNC1CCCCC1)OC(=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4032 BRD-A97730597 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4326 BRD-A97730597 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4629 BRD-A97730597 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4868 BRD-A97730597 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44270 BRD-A97730597 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44654 BRD-A97730597 A549 10 uM 6 h 0.32 1.34 0.89 0.0 0.0 0.0
44801 BRD-A97730597 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45119 BRD-A97730597 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.18
45390 BRD-A97730597 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45920 BRD-A97730597 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46239 BRD-A97730597 PHH 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
46552 BRD-A97730597 SKB 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
51579 BRD-A97730597 MCF??7.00 10 uM 24 h 0.24 0.98 0.09 -0.31 -1.04 0.68
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).