CMap Candidate Details
Structure:
| CMap ID: | C02550 |
| Pert ID: | BRD-K01674964 |
| Compound Name: | histamine |
| Targets: | HRH1|HRH2|HRH3|HRH4 |
| MoA: | histamine receptor agonist |
| SMILES: | NCCc1c[nH]cn1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 122896 | BRD-K01674964 | HEK293 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.32 |
| 123021 | BRD-K01674964 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.46 | 15.35 |
| 123110 | BRD-K01674964 | MDAMB231 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.07 | 0.75 |
| 123182 | BRD-K01674964 | THP1 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.44 |
| 131209 | BRD-K01674964 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131245 | BRD-K01674964 | A549 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131280 | BRD-K01674964 | HA1E | 0.74 uM | 24 h | 0.17 | 0.73 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131305 | BRD-K01674964 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131327 | BRD-K01674964 | HT29 | 2.22 uM | 24 h | 0.33 | 1.38 | 0.97 | 0.32 | 1.13 | 0.84 |
| 131358 | BRD-K01674964 | HUVEC | 0.74 uM | 24 h | 0.23 | 0.96 | 0.07 | 0.0 | 0.0 | 0.0 |
| 131398 | BRD-K01674964 | MCF10A | 0.08 uM | 24 h | -0.17 | -0.72 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131437 | BRD-K01674964 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.96 |
| 131464 | BRD-K01674964 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.08 |
| 131496 | BRD-K01674964 | YAPC | 0.01 uM | 24 h | 0.22 | 0.9 | 0.03 | 0.0 | 0.0 | 0.0 |