CMap Candidate Details
Structure:
| CMap ID: | C02563 |
| Pert ID: | BRD-K98493452 |
| Compound Name: | honokiol |
| Targets: | ALOX5|PTGS1|PTGS2 |
| MoA: | AKT inhibitor |
| SMILES: | Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 25459 | BRD-K98493452 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.13 | 0.97 |
| 95331 | BRD-K98493452 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95447 | BRD-K98493452 | U2OS | 10 uM | 6 h | -0.23 | -0.98 | 0.12 | -0.46 | -1.54 | 15.35 |
| 127335 | BRD-K98493452 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127409 | BRD-K98493452 | HA1E | 0.04 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.35 | 1.24 | 1.24 |
| 127496 | BRD-K98493452 | JURKAT | 1.11 uM | 24 h | -0.31 | -1.28 | 0.77 | 0.0 | 0.0 | 0.0 |
| 127547 | BRD-K98493452 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127590 | BRD-K98493452 | PC3 | 3.33 uM | 24 h | 0.3 | 1.24 | 0.52 | 0.31 | 1.1 | 0.7 |
| 127666 | BRD-K98493452 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135358 | BRD-K98493452 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.91 | 0.23 |
| 135387 | BRD-K98493452 | HT29 | 0.03 uM | 24 h | 0.3 | 1.24 | 0.53 | 0.25 | 0.89 | 0.21 |
| 135462 | BRD-K98493452 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135491 | BRD-K98493452 | THP1 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |