CMap Candidate Details
Structure:
| CMap ID: | C02591 |
| Pert ID: | BRD-A98299281 |
| Compound Name: | hydroxytacrine-maleate-(r,s) |
| Targets: | ACHE |
| MoA: | cholinesterase inhibitor |
| SMILES: | Nc1c2C(O)CCCc2nc2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6715 | BRD-A98299281 | A375 | 10 uM | 24 h | 0.19 | 0.79 | 0.0 | -0.23 | -0.77 | 0.09 |
| 6970 | BRD-A98299281 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.93 | 0.27 |
| 7284 | BRD-A98299281 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 7613 | BRD-A98299281 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7826 | BRD-A98299281 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8265 | BRD-A98299281 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.91 | 0.31 |
| 8792 | BRD-A98299281 | VCAP | 10 uM | 6 h | -0.23 | -0.97 | 0.11 | -0.3 | -1.01 | 0.57 |
| 51910 | BRD-A98299281 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91000 | BRD-A98299281 | HUH7 | 15 uM | 72 h | 0.18 | 0.75 | 0.0 | 0.22 | 0.78 | 0.07 |
| 98124 | BRD-A98299281 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98323 | BRD-A98299281 | NEU | 10 uM | 24 h | 0.25 | 1.05 | 0.17 | -0.27 | -0.91 | 0.3 |