CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02599
Pert ID:	BRD-K29673530
Compound Name:	hypericin
Targets:
MoA:	tyrosine kinase inhibitor
SMILES:	Cc1cc(O)c2c3c1c1c(C)cc(O)c4c1c1c3c3c(c(O)cc(O)c3c2=O)c2c(O)cc(O)c(c12)c4=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5766	BRD-K29673530	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6534	BRD-K29673530	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37630	BRD-K29673530	ASC	10 uM	24 h	0.31	1.31	0.76	-0.31	-1.03	0.63
37890	BRD-K29673530	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
38457	BRD-K29673530	NPC	10 uM	24 h	0.21	0.88	0.02	0.3	1.07	0.63
38706	BRD-K29673530	PHH	10 uM	24 h	-0.24	-0.98	0.13	0.0	0.0	0.0
38937	BRD-K29673530	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96128	BRD-K29673530	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99814	BRD-K29673530	U2OS	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.99	0.5
119955	BRD-K29673530	A375	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.84	0.18
120031	BRD-K29673530	HA1E	10 uM	24 h	-0.24	-1.02	0.17	0.0	0.0	0.0
120060	BRD-K29673530	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120115	BRD-K29673530	HT29	0.04 uM	24 h	0.24	1.02	0.13	0.0	0.0	0.0
120159	BRD-K29673530	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.49
120192	BRD-K29673530	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120219	BRD-K29673530	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary