CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02619
Pert ID:	BRD-K14965640
Compound Name:	ibuprofen-(s)
Targets:	ASIC1\|BCL2\|CFTR\|FABP2\|PLAT\|PPARG\|PTGS1\|PTGS2\|SLC5A8\|THBD
MoA:	cyclooxygenase inhibitor
SMILES:	CC(C)Cc1ccc(cc1)[C@H](C)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4198	BRD-K14965640	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
4550	BRD-K14965640	HCC515	10 uM	6 h	0.25	1.03	0.13	-0.23	-0.76	0.07
4781	BRD-K14965640	PC3	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5042	BRD-K14965640	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44314	BRD-K14965640	A375	10 uM	6 h	0.0	0.0	0.0	-0.31	-1.03	0.63
44527	BRD-K14965640	A549	10 uM	24 h	0.0	0.0	0.0	-0.19	-0.65	0.01
44868	BRD-K14965640	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45172	BRD-K14965640	HEPG2	10 uM	6 h	-0.22	-0.92	0.06	-0.23	-0.76	0.08
45441	BRD-K14965640	HT29	10 uM	6 h	0.0	0.0	0.0	-0.17	-0.59	0.0
45983	BRD-K14965640	NPC	10 uM	24 h	-0.22	-0.92	0.06	-0.3	-1.02	0.59
46302	BRD-K14965640	PHH	10 uM	24 h	0.0	0.0	0.0	0.22	0.78	0.07
46618	BRD-K14965640	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
52134	BRD-K14965640	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
100126	BRD-K14965640	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary