CMap Candidate Details
Structure:
| CMap ID: | C02635 |
| Pert ID: | BRD-K59433843 |
| Compound Name: | ICI-192605 |
| Targets: | TBXA2R |
| MoA: | thromboxane receptor antagonist |
| SMILES: | OC(=O)CC\C=C/C[C@@H]1CO[C@@H](O[C@@H]1c1ccccc1O)c1ccccc1Cl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123806 | BRD-K59433843 | A375 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123847 | BRD-K59433843 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.16 | 0.9 |
| 123914 | BRD-K59433843 | HEK293 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.41 | -1.37 | 2.02 |
| 124015 | BRD-K59433843 | JURKAT | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124068 | BRD-K59433843 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.19 | 0.68 | 0.01 |
| 124100 | BRD-K59433843 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.19 |
| 124135 | BRD-K59433843 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124155 | BRD-K59433843 | PC3 | 10 uM | 24 h | -0.19 | -0.79 | 0.0 | 0.31 | 1.1 | 0.7 |
| 124197 | BRD-K59433843 | THP1 | 0.37 uM | 24 h | 0.27 | 1.12 | 0.26 | 0.0 | 0.0 | 0.0 |
| 124249 | BRD-K59433843 | YAPC | 10 uM | 24 h | 0.28 | 1.16 | 0.35 | -0.28 | -0.94 | 0.37 |
| 132172 | BRD-K59433843 | HA1E | 0.03 uM | 24 h | -0.22 | -0.92 | 0.06 | 0.19 | 0.69 | 0.01 |
| 132202 | BRD-K59433843 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.15 | 0.88 |
| 132238 | BRD-K59433843 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.45 |