CMap Candidate Details
Structure:
| CMap ID: | C02663 |
| Pert ID: | BRD-A67097164 |
| Compound Name: | ifosfamide |
| Targets: | CYP2A6|CYP2B6|CYP2C18|CYP2C19|CYP2C8|CYP2C9|CYP3A4|CYP3A5|CYP3A7|PTGS1 |
| MoA: | DNA alkylating agent |
| SMILES: | ClCCNP1(=O)OCCCN1CCCl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91432 | BRD-A67097164 | HUH7 | 12.5 uM | 72 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.05 |
| 124986 | BRD-A67097164 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.41 | 1.46 | 2.23 |
| 125063 | BRD-A67097164 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.09 | 0.68 |
| 125089 | BRD-A67097164 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125141 | BRD-A67097164 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.41 | 1.44 | 2.21 |
| 125189 | BRD-A67097164 | THP1 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132989 | BRD-A67097164 | A375 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.06 |
| 133025 | BRD-A67097164 | HA1E | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133079 | BRD-A67097164 | HEK293 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133105 | BRD-A67097164 | HELA | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133185 | BRD-A67097164 | JURKAT | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.87 | 0.17 |
| 133247 | BRD-A67097164 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.23 | 1.28 |
| 133275 | BRD-A67097164 | MDAMB231 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133329 | BRD-A67097164 | YAPC | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |